Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.47 |
| ▸ | ATP4A | P20648 | 3/20 | 0.42 |
| ▸ | ATP4B | P51164 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5760394 | 0.93 | HMOX1 (0.47) | HMOX1ATP4AATP4BCYP19A1NOS1 | |
| SCHEMBL5758029 | 0.88 | HMOX1 (0.59) | HMOX1ATP4AATP4BCYP19A1 | |
| SCHEMBL5761892 | 0.84 | HMOX1 (0.47) | HMOX1ATP4AATP4BCYP19A1NOS1 | |
| SCHEMBL5756471 | 0.84 | HMOX1 (0.48) | HMOX1CYP19A1NOS1KDM4ELMNA | |
| SCHEMBL5762170 | 0.83 | HMOX1 (0.58) | HMOX1ATP4AATP4BCYP19A1KDM4E | |
| SCHEMBL5761197 | 0.83 | ERBB2 (0.51) | HMOX1ATP4AATP4BCYP19A1NOS1 | |
| SCHEMBL5761192 | 0.83 | ERBB2 (0.51) | HMOX1ATP4AATP4BCYP19A1NOS1 | |
| SCHEMBL5761819 | 0.82 | HMOX1 (0.47) | HMOX1ATP4AATP4BNOS1KDM4E | |
| SCHEMBL5761248 | 0.81 | HMOX1 (0.47) | HMOX1ATP4AATP4BCYP19A1 | |
| SCHEMBL5757703 | 0.81 | HMOX1 (0.53) | HMOX1ATP4AATP4BCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |