Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753527 | 0.92 | NPC1 (0.39) | POLBHTTNPC1ALDH1A1HPGD | |
| SCHEMBL5753729 | 0.89 | ALDH1A1 (0.36) | POLBHTTNPC1ALDH1A1P2RX7 | |
| SCHEMBL5752573 | 0.89 | KDM4E (0.41) | POLBHTTALDH1A1P2RX7HPGD | |
| SCHEMBL5759242 | 0.89 | KDM4E (0.41) | POLBHTTALDH1A1P2RX7HPGD | |
| SCHEMBL5755757 | 0.89 | KDM4E (0.41) | POLBHTTALDH1A1P2RX7HPGD | |
| SCHEMBL5757202 | 0.88 | KDM4E (0.41) | POLBHTTALDH1A1P2RX7HPGD | |
| SCHEMBL5755085 | 0.88 | SMN1; SMN2 (0.40) | POLBHTTNPC1ALDH1A1HPGD | |
| SCHEMBL5757305 | 0.87 | REN (0.41) | POLBALDH1A1P2RX7HPGDCACNA1B | |
| SCHEMBL5754993 | 0.86 | ALDH1A1 (0.39) | ALDH1A1P2RX7CACNA1B | |
| SCHEMBL5756321 | 0.86 | CACNA1B (0.51) | POLBALDH1A1P2RX7HPGDPNLIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |