Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.35 |
| ▸ | CMA1 | P23946 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834315 | 0.76 | GSK3B (0.45) | AHRCMA1MAOBGSK3BCCNB2 | |
| SCHEMBL5343358 | 0.74 | HTR1A (0.44) | DRD2DRD3NR3C2 | |
| SCHEMBL253953 | 0.74 | AHR (0.52) | AHRCMA1GSK3BCCNB2CDK1 | |
| SCHEMBL20588667 | 0.73 | CMA1 (0.50) | AHRCMA1GSK3BCCNB2CDK1 | |
| SCHEMBL29502199 | 0.73 | CMA1 (0.50) | AHRCMA1GSK3BCCNB2CDK1 | |
| SCHEMBL9834708 | 0.71 | TDP2 (0.36) | AHRCMA1GAAGSK3BCCNB2 | |
| SCHEMBL2811609 | 0.70 | AHR (0.56) | AHRCMA1MAOBGAAPDK2 | |
| SCHEMBL29746650 | 0.70 | AHR (0.56) | AHRCMA1MAOBGAAPDK2 | |
| SCHEMBL259997 | 0.68 | MAOB (0.43) | AHRCMA1MAOBGAAPDK2 | |
| SCHEMBL261277 | 0.67 | AHR (0.48) | AHRCMA1GSK3BCCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706376-A1 | IMIDAZOLE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005054188-A1 | IMIDAZOLE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB, S.A. (BE) | 2005-06-16 | — | — | WO | disclosed |