Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757007 | 1.00 | OPRM1 (0.40) | OPRM1KCNH2OPRD1OPRK1HRH3 | |
| SCHEMBL5755267 | 0.81 | OPRM1 (0.58) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL5755274 | 0.81 | OPRM1 (0.58) | OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL6655630 | 0.76 | OPRD1 (0.47) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6655635 | 0.76 | OPRD1 (0.47) | OPRM1OPRD1OPRK1 | |
| SCHEMBL5754460 | 0.64 | OPRM1 (0.61) | OPRM1KCNH2OPRD1OPRK1GRIA2 | |
| SCHEMBL5754470 | 0.64 | OPRM1 (0.61) | OPRM1KCNH2OPRD1OPRK1GRIA2 | |
| SCHEMBL5752550 | 0.64 | OPRM1 (0.66) | OPRM1KCNH2OPRD1OPRK1LMNA | |
| SCHEMBL5754154 | 0.64 | OPRM1 (0.68) | OPRM1KCNH2OPRD1OPRK1MEN1 | |
| SCHEMBL5752558 | 0.64 | OPRM1 (0.66) | OPRM1KCNH2OPRD1OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140828-B1 | 3-AZABICYCLO¬3.1.0|HEXANE DERIVATIVES AS OPIATE RECEPTORS LIGANDS | PFIZER LTD (GB) | 2006-08-09 | — | — | EP | claimed |