Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HEXD | Q8WVB3 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758338 | 0.82 | ADORA2A (0.43) | ALDH1A1ADORA2AMEN1KMT2ACNR1 | |
| SCHEMBL5756342 | 0.81 | ADORA2A (0.56) | L3MBTL1ADORA2AMEN1KMT2ADYRK1A | |
| SCHEMBL5757230 | 0.79 | CNR1 (0.42) | ALDH1A1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL5757421 | 0.76 | NPC1 (0.47) | ALDH1A1ADORA2ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5757516 | 0.75 | CXCR2 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ACNR1 | |
| SCHEMBL5758378 | 0.75 | CNR1 (0.41) | ALDH1A1CNR1CNR2MAPTKDM4E | |
| SCHEMBL5758176 | 0.73 | PDE10A (0.53) | ALDH1A1L3MBTL1ADORA2ASMN1; SMN2MEN1 | |
| SCHEMBL2162225 | 0.68 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1PDE5ASMN1; SMN2MEN1 | |
| SCHEMBL109195 | 0.66 | TAAR1 (0.64) | ALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL3088812 | 0.65 | PDE5A (0.53) | ALDH1A1CYP1A2CYP3A4CYP2C9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194144-B1 | ANTIBACTERIAL COMPOUNDS | AFFINIUM PHARM INC (CA) | 2006-11-02 | — | — | EP | claimed |
| US-20030149089-A1 | Antibacterial compounds | SMITHKLINE BEECHAM CORPORATION | 2003-08-07 | — | — | US | claimed |
| EP-1194144-B1 | ANTIBACTERIAL COMPOUNDS | AFFINIUM PHARM INC (CA) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149089-A1 | Antibacterial compounds | MRPL21, MRPS28, SPOUT1 | ALDH1A1 388/4885CYP1A2 742/4885CYP3A4 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.