Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | CCR3 | P51677 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | CCR5 | P51681 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.57 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.57 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411295 | 0.92 | OPRM1 (0.64) | KCNH2CCR3SIGMAR1OPRM1PRMT6 | |
| Hydrochloric Acid SCHEMBL7402387 | 0.90 | OPRM1 (0.62) | KCNH2CCR3SIGMAR1OPRM1PRMT6 | |
| SCHEMBL7405685 | 0.83 | GRIN2B (0.59) | CCR3OPRM1HRH3GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7403851 | 0.82 | GRIN2B (0.58) | CCR3OPRM1GRIN2AGRIN2B | |
| Pimetine SCHEMBL1816328 | 0.81 | CCR3 (0.67) | KCNH2CCR3SIGMAR1OPRM1SLC6A2 | |
| SCHEMBL5757823 | 0.81 | CCR5 (0.75) | KCNH2CCR3SIGMAR1CCR5OPRM1 | |
| SCHEMBL5758268 | 0.81 | CCR5 (0.57) | KCNH2CCR3SIGMAR1CCR5OPRM1 | |
| SCHEMBL5755425 | 0.81 | KCNH2 (0.59) | KCNH2CCR3SIGMAR1CCR5OPRM1 | |
| Pimetine SCHEMBL636750 | 0.80 | CCR3 (0.65) | KCNH2CCR3SIGMAR1OPRM1PRMT6 | |
| Pimetine SCHEMBL30496149 | 0.80 | CCR3 (0.65) | KCNH2CCR3SIGMAR1OPRM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | claimed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | claimed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | claimed |
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |