Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758262 | 1.00 | ERBB2 (0.39) | ERBB2MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL5759912 | 0.85 | FFAR1 (0.43) | ERBB2MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL5759910 | 0.85 | FFAR1 (0.43) | ERBB2MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL5760787 | 0.81 | LTB4R (0.37) | ERBB2MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL7959564 | 0.81 | LTB4R (0.37) | ERBB2MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL5761322 | 0.81 | ERBB2 (0.52) | ERBB2MINK1LTA4HEPHX2 | |
| SCHEMBL5761318 | 0.81 | ERBB2 (0.52) | ERBB2MINK1LTA4HEPHX2 | |
| SCHEMBL5758381 | 0.81 | CYP24A1 (0.43) | — | |
| SCHEMBL5761435 | 0.81 | CYP24A1 (0.43) | — | |
| SCHEMBL5758992 | 0.80 | CYP4F2 (0.42) | KMT2AHPGDL3MBTL1KDM4ELTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |