SCHEMBL7959564

SCHEMBL7959564

CS(=O)(=O)OCCCc1ccc(SCc2coc(C=Cc3ccccc3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 8/20 0.37
CYP24A1 Q07973 1/20 0.36
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
ERBB2 P04626 5/20 0.34
MINK1 Q8N4C8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
DAGLA Q9Y4D2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5760787 1.00 LTB4R (0.37) LTB4RCYP24A1PPARGPPARAERBB2
SCHEMBL5762454 0.85 ERBB2 (0.47) CYP24A1PPARGPPARAERBB2MINK1
SCHEMBL5762449 0.85 ERBB2 (0.47) CYP24A1PPARGPPARAERBB2MINK1
SCHEMBL5762604 0.83 ERBB2 (0.49) CYP24A1PPARGPPARAERBB2MINK1
SCHEMBL5757663 0.83 ERBB2 (0.49) CYP24A1PPARGPPARAERBB2MINK1
SCHEMBL5757306 0.82 ERBB2 (0.49) LTB4RCYP24A1PPARGPPARAERBB2
SCHEMBL5757310 0.82 ERBB2 (0.49) LTB4RCYP24A1PPARGPPARAERBB2
SCHEMBL5761048 0.82 ERBB2 (0.49) LTB4RCYP24A1PPARGPPARAERBB2
SCHEMBL5761043 0.82 ERBB2 (0.49) LTB4RCYP24A1PPARGPPARAERBB2
SCHEMBL5758259 0.81 ERBB2 (0.39) LTB4RERBB2MINK1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211215-B1 AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-03 US disclosed
EP-0912562-A1 HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1999-05-06 EP disclosed
WO-1998003505-A2 HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-01-29 WO disclosed