Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | FNTA | P49354 | 11/20 | 0.43 |
| ▸ | FNTB | P49356 | 11/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754306 | 0.87 | CYP3A4 (0.55) | CYP3A4FNTAFNTBPGGT1BRORC | |
| SCHEMBL5753828 | 0.76 | FNTA (0.71) | CYP3A4FNTAFNTBRORC | |
| SCHEMBL5756788 | 0.76 | CYP3A4 (0.70) | CYP3A4FNTAFNTBPGGT1B | |
| SCHEMBL5755627 | 0.76 | FNTA (0.55) | CYP3A4FNTAFNTBPGGT1BRORC | |
| SCHEMBL5756776 | 0.75 | CYP3A4 (0.60) | CYP3A4FNTAFNTBPGGT1B | |
| SCHEMBL5509171 | 0.73 | FNTA (0.73) | CYP3A4FNTAFNTBPGGT1B | |
| SCHEMBL5071351 | 0.72 | FNTA (0.64) | CYP3A4FNTAFNTBPGGT1B | |
| SCHEMBL5736856 | 0.71 | FNTA (0.73) | CYP3A4FNTAFNTBPGGT1BRORC | |
| SCHEMBL5755701 | 0.69 | FNTA (0.54) | CYP3A4FNTAFNTBPGGT1BRORC | |
| SCHEMBL5734468 | 0.68 | CYP3A4 (0.53) | CYP3A4FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351954-B1 | FARNESYL TRANSFERASE INHIBITING 4-HETEROCYCLYL-QUINOLINE AND QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2006-05-03 | — | — | EP | claimed |