Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111872 | 0.97 | HCAR2 (0.46) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL5204506 | 0.95 | HCAR2 (0.45) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| Formaldehyde SCHEMBL28038712 | 0.93 | HCAR2 (0.43) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| Nitrous Acid SCHEMBL28928125 | 0.89 | HCAR2 (0.41) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| SCHEMBL16135687 | 0.82 | HCAR2 (0.39) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| SCHEMBL6125229 | 0.82 | ALDH1A1 (0.46) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| SCHEMBL3667385 | 0.82 | ALDH1A1 (0.42) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| SCHEMBL31446649 | 0.82 | HCAR2 (0.39) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| SCHEMBL21825962 | 0.82 | HDAC3 (0.41) | HCAR2DPP4HDAC3HDAC4HDAC1 | |
| SCHEMBL844329 | 0.79 | HCAR2 (0.37) | HCAR2DPP4HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292593-B1 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2006-06-07 | — | — | EP | disclosed |
| US-6924298-B2 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | DOW AGROSCIENCES LLC (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040006108-A1 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | TISDELL FRANCIS EUGENE (US) | 2004-01-08 | — | — | US | disclosed |
| EP-1292593-A2 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | Dow AgroSciences LLC (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001098296-A2 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006108-A1 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | TARS2, TTL, TARS1 | HCAR2 4635/4885DPP4 41/4885HDAC3 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.