Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391356 | 0.81 | GAA (0.52) | KMT2AALDH1A1GAANPSR1LMNA | |
| SCHEMBL5727238 | 0.75 | KCNA5 (0.41) | KMT2AALDH1A1GAAMEN1LMNA | |
| SCHEMBL6370877 | 0.75 | KMT2A (0.40) | KMT2AALDH1A1GAANPSR1LMNA | |
| SCHEMBL5760942 | 0.74 | KMT2A (0.45) | KMT2AALDH1A1GAANPSR1LMNA | |
| SCHEMBL5368616 | 0.72 | ALDH1A1 (0.56) | KMT2AALDH1A1GAALMNAKDM4E | |
| SCHEMBL5361897 | 0.72 | KMT2A (0.43) | KMT2AALDH1A1GAALMNAKDM4E | |
| SCHEMBL5762956 | 0.71 | KMT2A (0.44) | KMT2AALDH1A1GAANPSR1LMNA | |
| SCHEMBL14578750 | 0.70 | LMNA (0.61) | KMT2AALDH1A1GAALMNA | |
| SCHEMBL11485663 | 0.70 | KMT2A (0.54) | KMT2AALDH1A1GAANPSR1MEN1 | |
| SCHEMBL28401707 | 0.70 | ALDH1A1 (0.47) | KMT2AALDH1A1GAAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556371-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | WINSTON PHARMACEUTICALS LLC (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1556371-A2 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | Winston Pharmaceuticals LLC (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004009583-A2 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | GARST MICHAEL E (US) | 2004-01-29 | — | — | WO | disclosed |