SCHEMBL576106

SCHEMBL576106

CC1OC(=O)C1(c1cccc2ccccc12)c1cccc2ccccc12.Cc1cccc(C2(c3cccc(C)c3C)C(=O)OC2C)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
CYP2A6 P11509 2/20 0.39
CYP1A2 P05177 3/20 0.37
TSHR P16473 2/20 0.37
KDM4E B2RXH2 5/20 0.33
MAPT P10636 4/20 0.33
MAPK1 P28482 4/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 1/20 0.33
NPSR1 Q6W5P4 3/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
CCR2 P41597 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
TAAR1 Q96RJ0 1/20 0.31
LMNA P02545 1/20 0.31
SLC6A2 P23975 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL980483 0.90 MAPT (0.39) ALDH1A1CYP2A6KDM4EMAPTMAPK1
SCHEMBL981167 0.89 CCR2 (0.38) CYP1A2TSHRNPSR1CYP3A4CYP2C9
SCHEMBL576548 0.66 SLC6A3 (0.38) KDM4EMAPTMAPK1KMT2AMEN1
SCHEMBL577590 0.64 CCR2 (0.41) CYP1A2TSHRKDM4ENPSR1CYP3A4
SCHEMBL576569 0.64 SLC6A3 (0.39) KDM4EMAPTMAPK1KMT2AMEN1
SCHEMBL576003 0.63 SLC6A3 (0.36) CYP1A2KDM4EMAPTMAPK1KMT2A
SCHEMBL9496870 0.62 CYP2A6 (0.85) ALDH1A1CYP2A6CYP1A2TSHRMAPK1
SCHEMBL576492 0.62 CREBBP (0.38) CYP1A2TSHRKDM4ENPSR1CYP3A4
SCHEMBL10684163 0.60 CYP2A6 (1.00) ALDH1A1CYP2A6CYP1A2TSHRMAPK1
SCHEMBL29903166 0.60 CYP2A6 (1.00) ALDH1A1CYP2A6CYP1A2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418723-A1 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same Mitsubishi Chemical Corporation (JP) 2012-02-15 EP disclosed