Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.36 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762716 | 1.00 | CYP2C9 (0.39) | CYP2C9THRBAKR1C3KMT2AMEN1 | |
| SCHEMBL5762701 | 0.99 | CYP2C9 (0.39) | CYP2C9THRBAKR1C3KMT2AMEN1 | |
| SCHEMBL5762257 | 0.94 | CYP2C9 (0.41) | CYP2C9THRBAKR1C3KMT2AMEN1 | |
| SCHEMBL5762706 | 0.94 | CYP2C9 (0.39) | CYP2C9THRBAKR1C3KMT2AMEN1 | |
| SCHEMBL5762238 | 0.93 | CYP2C9 (0.40) | CYP2C9THRBAKR1C3KMT2AMEN1 | |
| SCHEMBL7231795 | 0.92 | CYP2C9 (0.43) | CYP2C9KMT2AMEN1BRS3HSD17B10 | |
| SCHEMBL7013702 | 0.91 | CYP2C9 (0.43) | CYP2C9KMT2AMEN1BRS3HSD17B10 | |
| SCHEMBL5762654 | 0.90 | CYP2C9 (0.39) | CYP2C9THRBKMT2AMEN1BRS3 | |
| SCHEMBL7225643 | 0.89 | CYP2C9 (0.43) | CYP2C9KMT2AMEN1BRS3HSD17B10 | |
| SCHEMBL5762633 | 0.89 | CYP2C9 (0.39) | CYP2C9THRBKMT2AMEN1BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298205-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS RELATED TO GASTRIC ACID SECRETION | SHEN JIE | 2010-11-25 | — | — | US | disclosed |
| US-20100298205-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS RELATED TO GASTRIC ACID SECRETION | SHEN JIE | 2010-11-25 | — | — | US | disclosed |
| US-20090048302-A1 | Methods and compositions for the treatment of conditions related to gastric acid secretion | ALLERGAN, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| US-20090048302-A1 | Methods and compositions for the treatment of conditions related to gastric acid secretion | ALLERGAN, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| EP-1556371-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR | WINSTON PHARMACEUTICALS LLC (US) | 2006-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298205-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS RELATED TO GASTRIC ACID SECRETION | ABCB11, SLC10A2, SLC47A2 | CYP2C9 436/4885THRB 2086/4885AKR1C3 1879/4885 |
| US-20090048302-A1 | Methods and compositions for the treatment of conditions related to gastric acid secretion | ABCB11, SLC10A2, SLC47A2 | CYP2C9 436/4885THRB 2086/4885AKR1C3 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.