Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761228 | 0.83 | DRD2 (0.40) | DRD2DRD3SLC9A3KDM1AMCHR1 | |
| SCHEMBL14559957 | 0.76 | DRD2 (0.55) | DRD2DRD3HTR1A | |
| SCHEMBL31717769 | 0.73 | DGAT1 (0.44) | SLC9A3DGAT1MCHR1 | |
| SCHEMBL14559963 | 0.72 | DRD2 (0.59) | DRD2DRD3HTR1A | |
| SCHEMBL14559956 | 0.72 | DRD2 (0.63) | DRD2DRD3HTR1A | |
| SCHEMBL14559960 | 0.72 | DRD2 (0.47) | DRD2DRD3HTR1A | |
| SCHEMBL14559974 | 0.71 | HSD17B10 (0.51) | DRD2DRD3 | |
| SCHEMBL14559966 | 0.70 | DRD2 (0.63) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL14559972 | 0.69 | GAA (0.54) | DRD2DRD3HTR1A | |
| SCHEMBL14559967 | 0.69 | DRD2 (0.44) | DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638932-A1 | NOVEL PIPERAZINYL-ARYLOXY AND PIPERAZINYL-HETEROARYLOXY-N-ARYL LACTAMS | Pfizer Products Inc. (US) | 2006-03-29 | — | — | EP | claimed |
| WO-2004110994-A1 | NOVEL PIPERAZINYL-ARYLOXY AND PIPERAZINYL-HETEROARYLOXY-N-ARYL LACTAMS | PFIZER PRODUCTS INC. (US) | 2004-12-23 | — | — | WO | claimed |