Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ZNF207 | O43670 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763317 | 1.00 | PGR (0.36) | PGRCTSSHSD11B1HTTLMNA | |
| SCHEMBL5763319 | 1.00 | PGR (0.36) | PGRCTSSHSD11B1HTTLMNA | |
| SCHEMBL5790318 | 0.81 | MAPT (0.52) | PGRLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5764197 | 0.81 | MAPT (0.52) | PGRLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5791086 | 0.81 | MAPT (0.52) | PGRLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL521737 | 0.77 | SCD (0.43) | CTSSKCNJ1KMT2AMEN1PKM | |
| SCHEMBL5761399 | 0.74 | PGR (0.44) | PGRCTSSLMNAKMT2AZNF207 | |
| SCHEMBL5761394 | 0.74 | PGR (0.44) | PGRCTSSLMNAKMT2AZNF207 | |
| SCHEMBL7383256 | 0.71 | ALDH1A1 (0.41) | HSD11B1HTTLMNAKCNJ1KMT2A | |
| SCHEMBL5761621 | 0.68 | MAPT (0.43) | HTTLMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656357-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005005399-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |