Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122102 | 0.82 | AKR1C2 (0.35) | ALDH1A1KDM4EKMT2ATYK2MAPT | |
| SCHEMBL5465425 | 0.78 | TYK2 (0.42) | ALDH1A1KMT2ATYK2MAPTJAK2 | |
| SCHEMBL5763251 | 0.73 | CYP1A2 (0.35) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL8427153 | 0.73 | KDM4E (0.51) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E | |
| SCHEMBL4115272 | 0.72 | BCL2 (0.36) | — | |
| SCHEMBL15145241 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL15141254 | 0.72 | DPP4 (0.36) | ALDH1A1KDM4EMAPK1SMN1; SMN2HSD17B10 | |
| SCHEMBL4119971 | 0.72 | ALDH1A1 (0.49) | TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E | |
| SCHEMBL5766175 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL15145242 | 0.71 | DPP4 (0.35) | ALDH1A1KDM4EMAPK1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638962-A2 | SUBSTITUTED OXYARENES UND DEREN VERWENDUNG ZUR BEKÄMPFUNG VON SCHÄDLINGEN | Bayer CropScience AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004099197-A2 | SUBSTITUTED OXYARENES, AND USE THEREOF FOR CONTROLLING PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-11-18 | — | — | WO | disclosed |