Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 20/20 | 0.56 |
| ▸ | PLA2G10 | O15496 | 5/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 5/20 | 0.55 |
| ▸ | PLA2G2E | Q9NZK7 | 5/20 | 0.55 |
| ▸ | PLA2G2D | Q9UNK4 | 4/20 | 0.55 |
| ▸ | PLA2G5 | P39877 | 4/20 | 0.49 |
| ▸ | PLA2G2F | Q9BZM2 | 3/20 | 0.49 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.48 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.48 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.48 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.48 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762562 | 0.88 | PLA2G2A (0.59) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL5763443 | 0.86 | PLA2G2A (0.55) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL7019808 | 0.85 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL7150065 | 0.79 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL7147626 | 0.77 | PLA2G2A (0.48) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL7151654 | 0.76 | PLA2G2A (0.48) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL5763594 | 0.76 | PLA2G2A (0.61) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL5766238 | 0.76 | PLA2G2A (0.55) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL2157246 | 0.74 | PLA2G2A (0.80) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D | |
| SCHEMBL5764980 | 0.74 | PLA2G2A (0.58) | PLA2G2APLA2G10PLA2G1BPLA2G2EPLA2G2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |