SCHEMBL576359

SCHEMBL576359

FC1CCCC[C]1c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CYP11B2 P19099 1/20 0.35
NOS1 P29475 2/20 0.34
NOS2 P35228 2/20 0.34
MCL1 Q07820 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
SRC P12931 1/20 0.33
MAPT P10636 1/20 0.33
SLC18A3 Q16572 1/20 0.33
TSHR P16473 1/20 0.32
POLB P06746 1/20 0.32
CASP3 P42574 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2013779 0.94 ALDH1A1 (0.33) CHRNB4CHRNA3CYP11B2ALDH1A1SLC18A3
SCHEMBL2537360 0.85 ALDH1A1 (0.36) CHRNB4CHRNA3CYP11B2ALDH1A1MEN1
SCHEMBL11504128 0.77 DDB1 (0.42) NOS1NOS2ALDH1A1MEN1KMT2A
SCHEMBL5534036 0.77 HRH2 (0.41) CHRNB4CHRNA3NOS1NOS2MCL1
SCHEMBL7700085 0.77 CHRNB4 (0.41) CHRNB4CHRNA3NOS1NOS2MCL1
SCHEMBL18549967 0.75 ALDH1A1 (0.36) CHRNB4CHRNA3CYP11B2NOS1NOS2
SCHEMBL4618385 0.75 SLC18A3 (0.39) CHRNB4CHRNA3NOS1NOS2MCL1
SCHEMBL6367893 0.75 CHRNB4 (0.35) CHRNB4CHRNA3CYP11B2NOS1NOS2
SCHEMBL170541 0.73 IGF1R (0.41) CHRNB4CHRNA3NOS1NOS2ALDH1A1
SCHEMBL17652437 0.72 ALDH1A1 (0.42) ALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418723-A1 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same Mitsubishi Chemical Corporation (JP) 2012-02-15 EP disclosed
EP-2378602-A2 Nonaqueous electrolyte for recherable battery, and recharchable battery with nonaqueous electrolyte Mitsubishi Chemical Corporation (JP) 2011-10-19 EP disclosed