Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CALML3 | P27482 | 1/20 | 0.30 |
| ▸ | SDHA | P31040 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3029329 | 1.00 | MAOA (0.35) | MAOAF10GRIN1GRIN2BBTK | |
| SCHEMBL3039686 | 0.91 | MAOA (0.45) | MAOAF10BTK | |
| SCHEMBL3044448 | 0.90 | MAOA (0.38) | MAOAF10GRIN1GRIN2BBTK | |
| SCHEMBL3033096 | 0.90 | MAOA (0.42) | MAOAF10CALML3 | |
| SCHEMBL3029331 | 0.88 | MAOA (0.36) | MAOAF10GRIN1GRIN2BBTK | |
| SCHEMBL3029334 | 0.83 | MAOA (0.36) | MAOA | |
| SCHEMBL5763629 | 0.83 | MAOA (0.36) | MAOA | |
| SCHEMBL3035217 | 0.81 | MAOA (0.43) | MAOACALML3 | |
| SCHEMBL5763143 | 0.81 | MAOA (0.43) | MAOACALML3 | |
| SCHEMBL5767289 | 0.81 | MAOA (0.48) | MAOAF10BTKCALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-B1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN CO LLC (US) | 2006-10-11 | — | — | EP | disclosed |