SCHEMBL5763666

SCHEMBL5763666

O=C1CCC(c2ccc(N3C[C@H](CNC(=S)C(F)F)OC3=O)cc2)CN1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 19/20 0.48
F2 P00734 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5761788 0.87 MAOB (0.44) F10
SCHEMBL5763015 0.85 MAOB (0.40) F10
SCHEMBL5763783 0.85 F10 (0.46) F10F2
SCHEMBL5763117 0.85 F10 (0.54) F10F2
SCHEMBL5762883 0.85 F10 (0.53) F10
SCHEMBL5761391 0.83 F10 (0.54) F10F2
SCHEMBL5737363 0.82 F10 (0.48) F10F2
SCHEMBL6309055 0.82 F10 (0.50) F10F2
SCHEMBL6309049 0.82 F10 (0.50) F10F2
SCHEMBL6308013 0.81 F10 (0.49) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7094900-B2 N-Aryl-2-oxazolidinones and their derivatives PHARMACIA & UPJOHN COMPANY LLC (US) 2006-08-22 US claimed
EP-1539745-B1 N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES PHARMACIA & UPJOHN CO LLC (US) 2006-03-29 EP claimed
US-20040072873-A1 N-Aryl-2-oxazolidinones and their derivatives GADWOOD ROBERT C (US) 2004-04-15 US claimed
US-7094900-B2 N-Aryl-2-oxazolidinones and their derivatives PHARMACIA & UPJOHN COMPANY LLC (US) 2006-08-22 US disclosed
EP-1539745-B1 N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES PHARMACIA & UPJOHN CO LLC (US) 2006-03-29 EP disclosed
EP-1539745-A1 N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES Pharmacia & Upjohn Company LLC (US) 2005-06-15 EP disclosed
US-20040072873-A1 N-Aryl-2-oxazolidinones and their derivatives GADWOOD ROBERT C (US) 2004-04-15 US disclosed
WO-2004014897-A1 N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES PHARMACIA & UPJOHN COMPANY LLC (US) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040072873-A1 N-Aryl-2-oxazolidinones and their derivatives OXA1L, NDUFS7, NDUFS6 F10 4763/4885F2 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.