NDUFS7 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20
SCHEMBL8490937	0.53	3/20

Clinical trials — most relevant to NDUFS7 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)	PHASE3	WITHDRAWN
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Mitoquines in COPD	nan	UNKNOWN
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
Diagnostic Odyssey Survey 2	nan	COMPLETED
Assessment of Follicular Fluid Level of Coenzyme Q10 in Women Undergoing ICSI	nan	UNKNOWN
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
EPI-743 for Mitochondrial Respiratory Chain Diseases	nan	NO_LONGER_AVAILABLE
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Pharmacokinetic Study on Three Formulations of Coenzyme Q10 With Different Carriers	nan	UNKNOWN
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Cardiac Mitochondrial Function in Explanted Human Hearts	nan	UNKNOWN
Impact of Iron Deficiency and Its Correction on Mitochondrial Metabolism of the Cardiomyocyte (MitoCardioFer)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFS7 binder may also engage these)

Protein	Name	Similarity
Q0MQI0	—	1.000	Q0MQI0 →
Q0MQH9	—	1.000	Q0MQH9 →
P0CB83	—	1.000	P0CB83 →
P0CB84	—	1.000	P0CB84 →
Q43844	—	1.000	Q43844 →
C0RIE0	—	1.000	C0RIE0 →
Q8G1B6	—	1.000	Q8G1B6 →
Q2YNC8	—	1.000	Q2YNC8 →
Q215I4	—	1.000	Q215I4 →
Q9DC70	—	1.000	Q9DC70 →
A6X1N3	—	0.999	A6X1N3 →
B0CLD0	—	0.999	B0CLD0 →
O47950	—	0.999	O47950 →
Q3SRE4	—	0.999	Q3SRE4 →
Q8YGK1	—	0.999	Q8YGK1 →
Q1BBP4	—	0.999	Q1BBP4 →
Q57DV0	—	0.999	Q57DV0 →
B2S544	—	0.999	B2S544 →
Q135X5	—	0.998	Q135X5 →
Q94360	—	0.998	Q94360 →
A4SF47	—	0.998	A4SF47 →
A1USW8	—	0.998	A1USW8 →
B7KQ65	—	0.997	B7KQ65 →
Q72NT7	—	0.997	Q72NT7 →
A8XFG2	—	0.997	A8XFG2 →
Q13BH4	—	0.997	Q13BH4 →
Q4UWB7	—	0.997	Q4UWB7 →
A5FX09	—	0.997	A5FX09 →
Q0APY9	—	0.997	Q0APY9 →
Q72GC9	—	0.997	Q72GC9 →