Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193587 | 0.92 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL25401566 | 0.84 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL192613 | 0.83 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL22280436 | 0.83 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5769537 | 0.83 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL193523 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL192156 | 0.82 | GRM5 (0.71) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL193516 | 0.82 | GRM5 (0.71) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL193106 | 0.82 | GRM5 (0.71) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL193158 | 0.82 | HSD11B1 (0.70) | ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685105-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005044797-A1 | ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-05-19 | — | — | WO | disclosed |