Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766687 | 0.91 | KDR (0.44) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5767694 | 0.90 | MAPT (0.42) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5764091 | 0.86 | IRAK4 (0.40) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5766182 | 0.85 | FGFR1 (0.43) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5764431 | 0.84 | GAA (0.41) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5766162 | 0.82 | KDR (0.46) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5767045 | 0.80 | BRAF (0.39) | MAPTKDM4EALDH1A1HPGDFGFR1 | |
| SCHEMBL5763180 | 0.78 | IRAK4 (0.48) | MAPTKDM4EALDH1A1HPGDFGFR1 | |
| SCHEMBL5767256 | 0.77 | KDR (0.47) | MAPTKDM4EALDH1A1HPGDFGFR1 | |
| SCHEMBL5767103 | 0.77 | BRAF (0.40) | MAPTKDM4EALDH1A1HPGDFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235825-B1 | NOVEL BENZOIMIDAZOLE DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | PFIZER PROD INC (US) | 2006-01-25 | — | — | EP | claimed |