Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.34 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.34 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.34 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749611 | 0.72 | FFAR4 (0.35) | BCHEACHELMNAKMT2AALDH1A1 | |
| SCHEMBL1749181 | 0.71 | HDAC3 (0.39) | BCHEACHEKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1749772 | 0.70 | ALDH1A1 (0.38) | BCHEACHEALDH1A1RAB9APOLM | |
| SCHEMBL1750306 | 0.69 | RAB9A (0.43) | BCHEACHEKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1750288 | 0.67 | HDAC3 (0.39) | BCHEACHEKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1749478 | 0.67 | PPARA (0.43) | — | |
| SCHEMBL1751993 | 0.65 | SMN1; SMN2 (0.62) | ACHEKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL67768 | 0.65 | HSD17B2 (0.43) | KMT2ARAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL15547532 | 0.64 | POLM (0.56) | KMT2ASMN1; SMN2POLMPOLKPOLL | |
| SCHEMBL17938479 | 0.64 | POLM (0.56) | KMT2ASMN1; SMN2POLMPOLKPOLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638964-A1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2006-03-29 | — | — | EP | claimed |
| WO-2004113331-A1 | NOVEL COMPOUNDS THAT MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-29 | — | — | WO | claimed |
| EP-1638964-A1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113331-A1 | NOVEL COMPOUNDS THAT MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-29 | — | — | WO | disclosed |