Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105391 | 0.81 | KDM4E (0.42) | CA1CA2CA4KDM4EASPH | |
| Hydrochloric Acid SCHEMBL9651745 | 0.79 | KDM4E (0.41) | CA1CA2CA4KDM4EASPH | |
| SCHEMBL5112165 | 0.79 | CA1 (0.34) | CA1CA2CA4KDM4EASPH | |
| SCHEMBL14791397 | 0.75 | AURKA (0.34) | CA1CA2CA4KDM4EASPH | |
| SCHEMBL6276742 | 0.75 | CA12 (0.38) | CA1CA2KDM4ETSHR | |
| SCHEMBL25199284 | 0.72 | KDM4E (0.38) | KDM4EASPHKDM8ADORA3TSHR | |
| SCHEMBL17185607 | 0.72 | SIRT6 (0.37) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL2338841 | 0.71 | NAPRT (0.38) | KDM4EASPHKDM8ADORA3TSHR | |
| SCHEMBL1004198 | 0.70 | CA1 (0.58) | CA1CA2CA4 | |
| SCHEMBL7146004 | 0.69 | CES2 (0.46) | CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882545-A | Substituted nicotinoylcarbamates as pesticides | BAYER CROPSCIENCE AG (DE) | 2006-12-20 | — | — | CN | disclosed |
| EP-1685111-A1 | SUBSTITUTED NICOTINOYLCARBAMATES AS PESTICIDES | Bayer CropScience AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047255-A1 | SUBSTITUTED NICOTINOYLCARBAMATES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-05-26 | — | — | WO | disclosed |