Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765799 | 0.80 | MAPK14 (0.52) | MAPK14RAB9ANPSR1 | |
| SCHEMBL5766666 | 0.80 | MAPK14 (0.50) | MAPK14RAB9A | |
| SCHEMBL4825090 | 0.75 | MAPK14 (0.67) | MAPK14APOBEC3G | |
| SCHEMBL5766104 | 0.75 | MAPK14 (0.56) | MAPK14APOBEC3G | |
| SCHEMBL14435024 | 0.75 | MAPK14 (0.36) | MAPK14 | |
| SCHEMBL5765435 | 0.74 | MAPK14 (0.48) | MAPK14HSD11B1 | |
| SCHEMBL5764666 | 0.74 | MAPK14 (0.42) | MAPK14APOBEC3G | |
| SCHEMBL4079695 | 0.73 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL14435664 | 0.73 | MAPK14 (0.34) | MAPK14 | |
| SCHEMBL10364829 | 0.73 | FLT1 (0.46) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321040-B2 | Triazolo-pyridines as anti-inflammatory compounds | PFIZER INC. (US) | 2008-01-22 | — | — | US | disclosed |
| US-7321040-B2 | Triazolo-pyridines as anti-inflammatory compounds | PFIZER INC. (US) | 2008-01-22 | — | — | US | disclosed |
| EP-1601672-B1 | TRIAZOLO-PYRIDINES AS ANTI-INFLAMMATORY COMPOUNDS | PFIZER PROD INC (US) | 2006-07-26 | — | — | EP | disclosed |