Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5764420 | 0.89 | KDM1A (0.40) | EGLN1 | |
| SCHEMBL2011682 | 0.78 | — | — | |
| SCHEMBL2011683 | 0.78 | — | — | |
| SCHEMBL16967412 | 0.77 | EGLN1 (0.47) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| Hydrochloric Acid SCHEMBL2239390 | 0.77 | EGLN1 (0.57) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL532127 | 0.77 | EGLN1 (0.47) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL15606429 | 0.77 | EGLN1 (0.47) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| Hydrochloric Acid SCHEMBL2239385 | 0.77 | EGLN1 (0.57) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL1703167 | 0.75 | EGLN1 (0.45) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL27168911 | 0.74 | MAPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377577-B1 | PYRROLE DERIVATES FOR TREATING CYTOKINE MEDIATED DISEASES | SANKYO CO (JP) | 2006-06-14 | — | — | EP | disclosed |