Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16967412 | 0.77 | EGLN1 (0.47) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL15606429 | 0.77 | EGLN1 (0.47) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL532127 | 0.77 | EGLN1 (0.47) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL5765192 | 0.75 | EGLN1 (0.45) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| Acetic Acid SCHEMBL28383924 | 0.72 | EGLN1 (0.42) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| Acetic Acid SCHEMBL28383926 | 0.72 | EGLN1 (0.42) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL2122649 | 0.69 | GAA (0.54) | TSHRNPSR1MAPTGAA | |
| Hydrochloric Acid SCHEMBL18765678 | 0.68 | TSHR (0.57) | TSHRMEN1KMT2ANPSR1MAPT | |
| SCHEMBL31743277 | 0.67 | EGLN1 (0.38) | EGLN1GRIA2TSHRNPSR1 | |
| Trifluoroacetic Acid SCHEMBL5764420 | 0.67 | KDM1A (0.40) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440526-B1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-11-12 | — | — | EP | disclosed |
| CN-102459176-B | 3-halo-(arly)-4-iminotetrahydropicolinates and application thereof as herbicides | DOW AGROSCIENCES LLC (US) | 2014-05-21 | — | — | CN | disclosed |
| US-8598086-B2 | 3-halo-(arly)-4-iminotetrahydropicolinates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | disclosed |
| EP-2440526-A1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144379-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-16 | — | — | WO | disclosed |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | HDHD5, ATL3, HCAR3 | EGLN1 1294/4885GRIA2 1024/4885CYP2D6 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.