Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15606429 | 1.00 | EGLN1 (0.47) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL16967412 | 1.00 | EGLN1 (0.47) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| Acetic Acid SCHEMBL28383924 | 0.94 | EGLN1 (0.42) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| Acetic Acid SCHEMBL28383926 | 0.94 | EGLN1 (0.42) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| Ethylene SCHEMBL16894867 | 0.79 | LMNA (0.32) | EGLN1GRIA2LMNA | |
| SCHEMBL7422071 | 0.77 | — | — | |
| SCHEMBL190462 | 0.77 | — | — | |
| SCHEMBL190463 | 0.77 | — | — | |
| SCHEMBL1703167 | 0.77 | EGLN1 (0.45) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 | |
| SCHEMBL5765192 | 0.77 | EGLN1 (0.45) | EGLN1GRIA2CYP2D6ALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440526-B1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2014-11-12 | — | — | EP | claimed |
| CN-102459176-A | 3-halo-(arly)-4-iminotetrahydropicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2012-05-16 | — | — | CN | claimed |
| EP-2440526-A1 | 3-HALO-6-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2012-04-18 | — | — | EP | claimed |
| WO-2010144379-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-16 | — | — | WO | claimed |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-12-09 | — | — | US | claimed |
| EP-0633928-B1 | MICRO-ORGANISMS, PREPARATION METHOD THEREFOR AND USES THEREOF | AVENTIS PHARMA SA (FR) | 2003-11-19 | — | — | EP | claimed |
| US-20030013616-A1 | Method for manufacturing outsole for footwear without applying external mold rubricant onto mold, and formulating composition therefor | PARK HEE-DAE (KR) | 2003-01-16 | — | — | US | claimed |
| WO-2002049822-A1 | METHOD FOR MANUFACTURING OUTSOLE FOR FOOTWEAR WITHOUT APPLYING EXTERNAL MOLD RUBRICANT ONTO MOLD, AND FORMULATING COMPOSITION THEREFOR | YAGNICK METHA (US) | 2002-06-27 | — | — | WO | claimed |
| CN-117659017-B | TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2026-05-15 | — | — | CN | disclosed |
| US-12577258-B2 | Macrocyclic compound | VERNALIS (R&D) LIMITED (GB) | 2026-03-17 | — | — | US | disclosed |
| US-12465660-B2 | Compositions and methods for cancer imaging and radiotherapy | VECT-HORUS (FR) | 2025-11-11 | — | — | US | disclosed |
| EP-4223368-B1 | MACROCYCLIC COMPOUNDS INCORPORATING PIPERIDINE AND QUINOLINE OR QUNAXOLINE AS IRAK-4 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY CONDITIONS | ASAHI KASEI PHARMA CORP (JP) | 2025-05-21 | — | — | EP | disclosed |
| CN-116348472-B | Macrocyclic compounds | 旭化成制药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| US-20240100204-A1 | COMPOSITIONS AND METHODS FOR CANCER IMAGING AND RADIOTHERAPY | VECT-HORUS (FR) | 2024-03-28 | — | — | US | disclosed |
| CN-1152338-A | Streptogramines and method for preparing same by mutasynthesis | RHONE POULENC RORER SA (FR) | 1997-06-18 | — | — | CN | disclosed |
| US-5610241-A | Reactive graft polymer with biodegradable polymer backbone and method for preparing reactive biodegradable polymers | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-03-11 | — | — | US | disclosed |
| WO-1996022775-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1996-08-01 | — | — | WO | disclosed |
| EP-0308983-A2 | NMR imaging with Mn(II) coordination compositions | SALUTAR, INC. (US) | 1989-03-29 | — | — | EP | disclosed |
| US-4330548-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-05-18 | — | — | US | disclosed |
| US-4296113-A | FOR TREATING HYPERTENSION BY INHIBITING ANGIOTENSIN CONVERTING ENZYME | E. R. SQUIBB & SONS, INC. (US) | 1981-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577258-B2 | Macrocyclic compound | IRAK1, IRAK4, IRAK2 | EGLN1 1028/4885GRIA2 392/4885CYP2D6 3138/4885 |
| US-20100311594-A1 | 3-HALO-(ARLY)-4-IMINOTETRAHYDROPICOLINATES AND THEIR USE AS HERBICIDES | HDHD5, ATL3, HCAR3 | EGLN1 1294/4885GRIA2 1024/4885CYP2D6 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.