Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14573160 | 0.91 | KCNH2 (0.48) | SLC2A1KCNH2 | |
| SCHEMBL5771874 | 0.89 | KCNH2 (0.41) | SLC2A1KCNH2 | |
| SCHEMBL5765930 | 0.87 | KCNH2 (0.53) | SLC2A1KCNH2 | |
| SCHEMBL5767030 | 0.87 | SLC2A1 (0.43) | SLC2A1KCNH2 | |
| SCHEMBL5764977 | 0.86 | HTR1D (0.53) | KCNH2HTR1AHTR1D | |
| SCHEMBL5764950 | 0.86 | HTR1A (0.51) | KCNH2HTR1AHTR1D | |
| SCHEMBL5765126 | 0.84 | SLC2A1 (0.43) | SLC2A1KCNH2 | |
| SCHEMBL5748163 | 0.78 | KCNH2 (0.44) | SLC2A1KCNH2 | |
| Oxalic Acid SCHEMBL5749364 | 0.77 | KCNH2 (0.42) | SLC2A1KCNH2 | |
| SCHEMBL14573154 | 0.77 | KCNH2 (0.43) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392686-B1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-10-18 | — | — | EP | claimed |