SCHEMBL5765576

SCHEMBL5765576

NC(=O)C1CN(c2ccc(C3=CCOCC3)c(F)c2)C(=O)O1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 11/20 0.59
CALML3 P27482 6/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3038323 1.00 MAOA (0.59) MAOACALML3
SCHEMBL8024116 0.85 MAOA (0.51) MAOACALML3
SCHEMBL13515439 0.84 MAOA (0.54) MAOACALML3
SCHEMBL5793840 0.84 MAOA (0.54) MAOACALML3
SCHEMBL5236431 0.83 CALML3 (0.62) MAOACALML3
SCHEMBL6395266 0.83 CALML3 (0.62) MAOACALML3
SCHEMBL5765713 0.82 MAOA (0.53) MAOACALML3
SCHEMBL3035266 0.82 MAOA (0.53) MAOACALML3
SCHEMBL13515909 0.82 MAOA (0.67) MAOACALML3
SCHEMBL3045998 0.82 MAOA (0.52) MAOACALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1478629-B1 N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS PHARMACIA & UPJOHN CO LLC (US) 2006-10-11 EP disclosed