Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 12/20 | 0.51 |
| ▸ | CALML3 | P27482 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SDHA | P31040 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236431 | 0.87 | CALML3 (0.62) | MAOACALML3MAOB | |
| SCHEMBL6395266 | 0.87 | CALML3 (0.62) | MAOACALML3MAOB | |
| SCHEMBL5765576 | 0.85 | MAOA (0.59) | MAOACALML3 | |
| SCHEMBL3038323 | 0.85 | MAOA (0.59) | MAOACALML3 | |
| SCHEMBL8006848 | 0.85 | MAOA (0.49) | MAOACALML3 | |
| SCHEMBL8024076 | 0.85 | GRM2 (0.43) | — | |
| SCHEMBL6396641 | 0.83 | MAOA (0.72) | MAOACALML3LMNAPTGS1MAOB | |
| SCHEMBL6396646 | 0.83 | MAOA (0.72) | MAOACALML3LMNAPTGS1MAOB | |
| SCHEMBL6686605 | 0.81 | F10 (0.57) | MAOACALML3LMNAPTGS1MAOB | |
| SCHEMBL6396609 | 0.80 | MAOA (0.47) | MAOACALML3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166056-A | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | PHARMACIA (US) | 2000-12-26 | — | — | US | disclosed |