Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328432 | 0.94 | USP14 (0.32) | USP14OPRM1OPRK1OPRL1 | |
| SCHEMBL29937133 | 0.77 | — | — | |
| SCHEMBL25416198 | 0.76 | — | — | |
| SCHEMBL22370767 | 0.75 | POLB (0.31) | OPRM1OPRK1OPRL1 | |
| SCHEMBL22370766 | 0.75 | POLB (0.31) | OPRM1OPRK1OPRL1 | |
| SCHEMBL22370636 | 0.73 | TET3 (0.30) | USP14 | |
| SCHEMBL25327796 | 0.73 | DPP4 (0.34) | — | |
| SCHEMBL13738244 | 0.71 | — | — | |
| SCHEMBL31065795 | 0.69 | CYP1A2 (0.31) | — | |
| SCHEMBL31506693 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732923-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005099706-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-10-27 | — | — | WO | disclosed |