Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765715 | 0.94 | USP14 (0.33) | USP14OPRM1OPRK1OPRL1 | |
| SCHEMBL29937133 | 0.82 | — | — | |
| SCHEMBL25416198 | 0.81 | — | — | |
| SCHEMBL25327796 | 0.77 | DPP4 (0.34) | — | |
| SCHEMBL22370636 | 0.77 | TET3 (0.30) | USP14 | |
| SCHEMBL22370767 | 0.76 | POLB (0.31) | OPRM1OPRK1OPRL1 | |
| SCHEMBL22370766 | 0.76 | POLB (0.31) | OPRM1OPRK1OPRL1 | |
| SCHEMBL23245392 | 0.70 | FFAR3 (0.33) | — | |
| SCHEMBL23245394 | 0.70 | FFAR3 (0.33) | — | |
| SCHEMBL30599614 | 0.69 | DAO (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365572-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2023-11-16 | — | — | US | disclosed |
| EP-4217359-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | Atrogi AB (SE) | 2023-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365572-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | CYP1B1, CYP11B1, CYP11B2 | USP14 3883/4885OPRM1 732/4885OPRK1 604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.