Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | C1R | P00736 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206937 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL14988800 | 0.82 | MGAM (0.47) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| SCHEMBL12881747 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| SCHEMBL9876453 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| SCHEMBL26965121 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| SCHEMBL28351456 | 0.79 | KMT2A (0.41) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL9767738 | 0.76 | ALDH1A1 (0.56) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| SCHEMBL14988958 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| SCHEMBL14988959 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TDP1MAOBMEN1KMT2A | |
| SCHEMBL15270786 | 0.75 | ALDH1A1 (0.53) | ALDH1A1TDP1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613612-A2 | BIOREDUCTIVELY-ACTIVATED PRODRUGS | Angiogene Pharmaceuticals Limited (GB) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004085421-A2 | BIOREDUCTIVELY-ACTIVATED PRODRUGS | ANGIOGENE PHARMACEUTICALS LIMITED (GB) | 2004-10-07 | — | — | WO | disclosed |