Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988958 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL14988703 | 0.82 | NPSR1 (0.39) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14988927 | 0.78 | MEN1 (0.53) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL5766529 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL21373453 | 0.75 | IKBKB (0.61) | ALDH1A1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL10966433 | 0.75 | HDAC3 (0.67) | ALDH1A1TDP1HDAC3HDAC4HDAC1 | |
| SCHEMBL12881747 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL9206937 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL14988800 | 0.73 | MGAM (0.47) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL14988947 | 0.71 | ADORA3 (0.45) | TDP1KMT2AF2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975411-B2 | Therapeutic agent for neurological diseases | NEUGEN PHARMA INC. (JP) | 2015-03-10 | — | — | US | disclosed |
| EP-2599776-B1 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES | NEUGEN PHARMA INC (JP) | 2014-10-15 | — | — | EP | disclosed |
| US-20130190363-A1 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2013-07-25 | — | — | US | disclosed |
| EP-2599776-A1 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES | Neugen Pharma Inc. (JP) | 2013-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190363-A1 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES | AIFM1, AIFM2, GPX4 | ALDH1A1 448/4885TDP1 1309/4885HDAC3 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.