Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.58 |
| ▸ | HTR2A | P28223 | 15/20 | 0.58 |
| ▸ | DRD2 | P14416 | 12/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765691 | 0.93 | HTR1A (0.58) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| SCHEMBL5767190 | 0.86 | HTR1A (0.61) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| SCHEMBL5764221 | 0.84 | HTR1A (0.62) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| SCHEMBL5795679 | 0.84 | HTR1A (0.62) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| SCHEMBL5763322 | 0.82 | HTR1A (0.62) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| SCHEMBL9752486 | 0.81 | HTR1A (0.63) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL9752511 | 0.79 | HTR1A (0.61) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| SCHEMBL9371546 | 0.79 | HTR1A (0.61) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| SCHEMBL5767158 | 0.79 | HTR1A (0.55) | HTR1AHTR7KCNH2HTR2ADRD2 | |
| SCHEMBL5764470 | 0.78 | HTR2A (0.51) | HTR1AKCNH2HTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701954-A1 | N-SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005066165-A1 | N-SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-07-21 | — | — | WO | disclosed |