Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 12/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.60 |
| ▸ | DRD2 | P14416 | 8/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9752511 | 0.98 | HTR1A (0.61) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| SCHEMBL9371546 | 0.94 | HTR1A (0.61) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| SCHEMBL9366195 | 0.91 | HTR1A (0.59) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL7412767 | 0.90 | HTR1A (0.62) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| SCHEMBL6404395 | 0.85 | HTR1A (0.64) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| SCHEMBL9366654 | 0.84 | HTR1A (0.60) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| SCHEMBL4885684 | 0.84 | HTR1A (0.64) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| SCHEMBL9367248 | 0.83 | HTR2A (0.68) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL4885489 | 0.83 | HTR1A (0.59) | HTR1AHTR7HTR2AKCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL7946844 | 0.83 | HTR1A (0.63) | HTR1AHTR7HTR2AKCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991000863-A1 | HETEROARYL PIPERAZINE ANTIPSYCHOTIC AGENTS | PFIZER INC. (US) | 1991-01-24 | — | — | WO | disclosed |