Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 6/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091362 | 0.85 | TBXAS1 (0.47) | QPCTTBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7609694 | 0.83 | QPCT (0.50) | QPCTTBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL278416 | 0.82 | QPCT (0.53) | QPCTTBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20987982 | 0.76 | TBXAS1 (0.49) | QPCTTBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4681306 | 0.73 | FDPS (0.50) | QPCTTBXAS1ALDH1A1FDPS | |
| SCHEMBL9241540 | 0.73 | TBXAS1 (0.50) | QPCTTBXAS1EGLN3ALDH1A1 | |
| SCHEMBL10240737 | 0.72 | QPCT (0.61) | QPCTTBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL46694 | 0.72 | — | — | |
| SCHEMBL10311722 | 0.72 | QPCT (0.50) | QPCTTBXAS1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5766575 | 0.72 | QPCT (0.38) | QPCTTBXAS1EGLN3ALDH1A1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625126-A1 | IMIDAZO AND THIAZOLOPYRIDINES AS JAK3 KINASE INHIBITORS | AstraZeneca AB (SE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004099204-A1 | IMIDAZO AND THIAZOLOPYRIDINES AS JAK3 KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-11-18 | — | — | WO | disclosed |