Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808614 | 0.82 | POLB (0.40) | STING1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6817003 | 0.80 | EDNRA (0.41) | PIK3CDSTING1L3MBTL1ESR1MEN1 | |
| SCHEMBL6812458 | 0.79 | L3MBTL1 (0.38) | L3MBTL1ALPLMEN1KMT2A | |
| SCHEMBL6808610 | 0.79 | STING1 (0.51) | STING1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6808644 | 0.79 | PDGFRA (0.35) | PIK3CDSTING1L3MBTL1ESR1ALPL | |
| SCHEMBL6812307 | 0.78 | KMT2A (0.39) | STING1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4790749 | 0.78 | L3MBTL1 (0.37) | NPC1RAB9AL3MBTL1ESR1MEN1 | |
| SCHEMBL6812764 | 0.78 | AURKB (0.33) | PIK3CDSTING1NPC1RAB9AL3MBTL1 | |
| SCHEMBL6811963 | 0.78 | KDM4E (0.39) | PIK3CDSTING1NPC1RAB9AL3MBTL1 | |
| SCHEMBL6812848 | 0.78 | EDNRA (0.47) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636212-A1 | CYCLOALKYLSULFANYL SUBSTITUTED BENZO[B]THIOPHENES AS THERAPEUTIC AGENTS | Warner-Lambert Company LLC (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108714-A1 | CYCLOALKYLSULFANYL SUBSTITUTED BENZO[B]THIOPHENES AS THERAPEUTIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-12-16 | — | — | WO | disclosed |