Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763527 | 0.94 | PIK3CD (0.40) | EDNRATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6812848 | 0.93 | EDNRA (0.47) | EDNRATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7061980 | 0.92 | RET (0.40) | EDNRATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6808644 | 0.92 | PDGFRA (0.35) | EDNRATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6812328 | 0.91 | EGFR (0.39) | EDNRATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6812307 | 0.91 | KMT2A (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4938115 | 0.90 | EDNRA (0.38) | EDNRATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4876565 | 0.90 | EDNRA (0.37) | EDNRATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5791121 | 0.89 | STING1 (0.36) | EDNRATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6812764 | 0.89 | AURKB (0.33) | EDNRAMEN1KMT2APOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248953-A1 | 3-Arylsulfanyl and 3-heteroarylsulfanyl substituted benzo[b]thiophenes as therapeutic agents | GOGLIOTTI ROCCO DEAN (US) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248953-A1 | 3-Arylsulfanyl and 3-heteroarylsulfanyl substituted benzo[b]thiophenes as therapeutic agents | SULT2A1, SULT1A1, SULT1E1 | EDNRA 2482/4885TUBB4A 3134/4885TUBB 2813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.