Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763764 | 0.87 | CACNA1F (0.46) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 | |
| SCHEMBL5767258 | 0.86 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 | |
| SCHEMBL5765288 | 0.84 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 | |
| SCHEMBL5764738 | 0.82 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 | |
| SCHEMBL5821119 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 | |
| SCHEMBL5767327 | 0.81 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 | |
| SCHEMBL5767506 | 0.81 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2ALOX12TP53MAPT | |
| SCHEMBL5765692 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 | |
| SCHEMBL5765306 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 | |
| SCHEMBL5765665 | 0.80 | CA1 (0.54) | ALDH1A1SMN1; SMN2ALOX12TP53HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116390-A1 | Hepatitis c virus inhibitors | LG LIFE SCIENCES LTD. (KR) | 2006-06-01 | — | — | US | disclosed |
| EP-1633725-A1 | HEPATITIS C VIRUS INHIBITORS | LG Life Sciences Ltd. (KR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004111013-A1 | HEPATITIS C VIRUS INHIBITORS | LG LIFE SCIENCES LTD. (KR) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116390-A1 | Hepatitis c virus inhibitors | HAVCR2, LIPC, FABP1 | ALDH1A1 1058/4885DAO 1626/4885SMN1; SMN2 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.