Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5765523 | 0.94 | ALDH1A1 (0.51) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL5765865 | 0.88 | ALDH1A1 (0.49) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL5768094 | 0.84 | ALDH1A1 (0.50) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL5766803 | 0.84 | ALDH1A1 (0.48) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL5766525 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL5767471 | 0.81 | DHFR (0.51) | ALDH1A1ALOX12DHFRCA1CA2 | |
| SCHEMBL5764058 | 0.80 | ALDH1A1 (0.51) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL5793194 | 0.80 | ALDH1A1 (0.47) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL5767177 | 0.80 | ALDH1A1 (0.49) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL5763881 | 0.80 | ALDH1A1 (0.45) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633725-A1 | HEPATITIS C VIRUS INHIBITORS | LG Life Sciences Ltd. (KR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004111013-A1 | HEPATITIS C VIRUS INHIBITORS | LG LIFE SCIENCES LTD. (KR) | 2004-12-23 | — | — | WO | disclosed |