Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803930 | 0.81 | P2RX7 (0.64) | P2RX7MEN1KMT2A | |
| SCHEMBL6617080 | 0.81 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL1804726 | 0.80 | P2RX7 (0.53) | P2RX7MEN1KMT2A | |
| SCHEMBL3837822 | 0.79 | P2RX7 (0.67) | P2RX7MEN1KMT2A | |
| SCHEMBL3837736 | 0.78 | P2RX7 (0.70) | P2RX7MEN1KMT2A | |
| SCHEMBL1804950 | 0.78 | P2RX7 (0.56) | P2RX7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3836582 | 0.78 | P2RX7 (0.66) | P2RX7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3837022 | 0.78 | P2RX7 (0.56) | P2RX7MEN1KMT2A | |
| SCHEMBL1813501 | 0.78 | P2RX7 (0.56) | P2RX7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3837908 | 0.77 | P2RX7 (0.55) | P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633717-A1 | NEW P2X7 RECEPTOR ANTAGONISTS AND THEIR USE | AstraZeneca AB (SE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004106305-A1 | NEW P2X7 RECEPTOR ANTAGONISTS AND THEIR USE | ASTRAZENECA AB (SE) | 2004-12-09 | — | — | WO | disclosed |