Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5769121 | 0.81 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL13958636 | 0.80 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL4896407 | 0.80 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL4508087 | 0.80 | P2RX7 (0.61) | P2RX7 | |
| Hydrochloric Acid SCHEMBL4493149 | 0.80 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL4511013 | 0.79 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL4497262 | 0.79 | P2RX7 (0.68) | P2RX7 | |
| Hydrochloric Acid SCHEMBL4511697 | 0.79 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL4504938 | 0.78 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL4508282 | 0.77 | P2RX7 (0.65) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490341-A1 | NOVEL ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003080579-A1 | NOVEL ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-10-02 | — | — | WO | disclosed |