Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5769288 | 0.91 | MAPT (0.41) | MAPTALDH1A1MAPK1HSD17B10HPGD | |
| SCHEMBL5946221 | 0.84 | SLC6A3 (0.47) | — | |
| SCHEMBL5769437 | 0.81 | ALDH2 (0.39) | MAPTALDH1A1MAPK1HPGDKMT2A | |
| SCHEMBL5946211 | 0.75 | SLC6A3 (0.47) | ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL5946257 | 0.70 | MAPT (0.47) | MAPTALDH1A1MAPK1HSD17B10HPGD | |
| SCHEMBL5946174 | 0.68 | CA12 (0.44) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL21296989 | 0.65 | ESR2 (0.56) | ALDH1A1HSD17B10KMT2AKDM4ENPC1 | |
| SCHEMBL5768912 | 0.65 | ALDH2 (0.42) | MAPTALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL24625565 | 0.63 | CA12 (0.58) | MAPTALDH1A1MAPK1HSD17B10HPGD | |
| SCHEMBL17817363 | 0.62 | SYK (0.48) | MAPTALDH1A1MAPK1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613635-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004073598-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A.U. (ES) | 2004-09-02 | — | — | WO | disclosed |