Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248649 | 0.86 | LMNA (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL35823 | 0.86 | PTGS2 (0.58) | MAPTKMT2AEGFRPTGS2MEN1 | |
| SCHEMBL3631102 | 0.85 | CA1 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6702060 | 0.85 | CA1 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13276414 | 0.82 | AR (0.57) | MAPTKMT2AERN1PTGS2RAB9A | |
| SCHEMBL3631211 | 0.81 | LMNA (0.56) | MAPTEGFRPTGS2GAAMGAM | |
| SCHEMBL6704931 | 0.80 | PTGS1 (0.55) | MAPTKMT2AERN1MEN1RAB9A | |
| SCHEMBL6883774 | 0.79 | HSD17B1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17559286 | 0.79 | ABL1 (0.61) | MAPTKMT2AEGFRERN1 | |
| SCHEMBL7501527 | 0.79 | EGFR (0.69) | MAPTKMT2AEGFRERN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | disclosed |
| WO-2022149925-A1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND USE THEREOF | 광주과학기술원 | 2022-07-14 | — | — | WO | disclosed |