Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 4/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312787 | 0.86 | LMNA (0.46) | L3MBTL1USP2PTGDR2 | |
| SCHEMBL6317353 | 0.86 | LMNA (0.46) | L3MBTL1USP2PTGDR2 | |
| SCHEMBL5747524 | 0.86 | LMNA (0.46) | L3MBTL1USP2PTGDR2 | |
| SCHEMBL14885392 | 0.81 | CRHBP (0.64) | L3MBTL1CRHBPCRHR2USP2GFER | |
| SCHEMBL23757987 | 0.79 | CRHBP (0.58) | L3MBTL1CRHBPCRHR2USP2GFER | |
| SCHEMBL23757669 | 0.79 | CRHBP (0.58) | L3MBTL1CRHBPCRHR2USP2GFER | |
| SCHEMBL23757665 | 0.79 | CRHBP (0.58) | L3MBTL1CRHBPCRHR2USP2GFER | |
| SCHEMBL6310767 | 0.75 | GLA (0.45) | L3MBTL1PTGDR2GLA | |
| SCHEMBL6319712 | 0.75 | GLA (0.45) | L3MBTL1PTGDR2GLA | |
| SCHEMBL6319715 | 0.75 | GLA (0.45) | L3MBTL1PTGDR2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638935-A1 | NK1 ANTAGONIST | Pfizer Products Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004110996-A1 | NK1 ANTAGONIST | PFIZER PRODUCTS INC. (US) | 2004-12-23 | — | — | WO | disclosed |