Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766840 | 0.88 | KDM4E (0.37) | ALDH1A1HTTNPSR1RXFP1NLRP3 | |
| SCHEMBL9573823 | 0.73 | CDK1 (0.39) | ALDH1A1NLRP3KDM4EHSD17B10GAA | |
| SCHEMBL5767967 | 0.72 | ALDH1A1 (0.44) | ALDH1A1RXFP1KDM4EHSD17B10GAA | |
| SCHEMBL4705953 | 0.70 | DAO (0.47) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL9573863 | 0.70 | CDK1 (0.39) | ALDH1A1KDM4EHSD17B10GAAHPGD | |
| SCHEMBL9232719 | 0.70 | KDM4E (0.41) | ALDH1A1NLRP3KDM4EHSD17B10GAA | |
| SCHEMBL9573812 | 0.68 | GAA (0.35) | ALDH1A1GAAHPGDCYP1A2CYP2C19 | |
| SCHEMBL9573874 | 0.68 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10ALOX15KMT2A | |
| SCHEMBL27215072 | 0.68 | NLRP3 (0.46) | ALDH1A1NLRP3KDM4ETSHRHSD17B10 | |
| SCHEMBL9937270 | 0.68 | NPC1 (0.52) | ALDH1A1HTTNPSR1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625129-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | Bayer HealthCare AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004099212-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2004-11-18 | — | — | WO | disclosed |