Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 11/20 | 0.42 |
| ▸ | FABP4 | P15090 | 7/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770046 | 0.87 | PLA2G2A (0.52) | PLA2G2AFABP4FABP3 | |
| SCHEMBL5767057 | 0.84 | FABP4 (0.46) | PLA2G2AFABP4FABP3PARP1 | |
| SCHEMBL5770181 | 0.83 | FABP4 (0.48) | PLA2G2AFABP4FABP3 | |
| SCHEMBL6393255 | 0.78 | PLA2G2A (0.47) | PLA2G2AFABP4FABP3 | |
| SCHEMBL27844984 | 0.78 | PLA2G2A (0.49) | PLA2G2A | |
| SCHEMBL29029760 | 0.77 | PLA2G2A (0.48) | PLA2G2A | |
| SCHEMBL5773611 | 0.76 | FABP4 (0.50) | FABP4FABP3 | |
| SCHEMBL5769684 | 0.76 | PLA2G2A (0.64) | PLA2G2A | |
| SCHEMBL6404040 | 0.76 | PLA2G2A (0.47) | PLA2G2AFABP4FABP3PARP1 | |
| SCHEMBL27845212 | 0.76 | PLA2G2A (0.44) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349836-B1 | TETRACYCLIC DERIVATIVES AS SPLA2 INHIBITORS | LILLY CO ELI (US) | 2006-06-14 | — | — | EP | disclosed |